Our brain is continuously influenced by our lifestyle (e.g., diet, pollution, physical activity, social life), playing a central role in interacting with the world around us.
This task requires a constant state of concentration and mental energy without forgetting, however, at any age, brain health depends not only on optimal mental and cognitive functions but also on maintaining brain integrity.1
Citicoline (CPD-Choline), defined as the “natural brain nutrient,” is an endogenous organic molecule known to promote brain health throughout the natural aging process.
As an intermediate metabolite, it acts as a precursor in the continuous synthesis of nerve cell membrane phospholipids, guaranteeing their integrity and fluidity, and the neurotransmitter acetylcholine, assisting in signaling functions for normal cholinergic neurotransmission.2 Therefore, citicoline simultaneously promotes brain membrane turnover and energy use by the brain with improved attention span, physical performance, and memory.3-5
Unfortunately, brain uptake of citicoline declines with advancing age, and its lower intake can contribute to age-related cognitive decline.6 This is why it is employed and supplemented as a versatile nootropic for brain health, preventing neurodegeneration.
The preferred choice for our dietary supplement Brain 5:5®, Cognizin® citicoline is patented by Kyowa Hakko Bio Co., Ltd. And produced through an innovative natural fermentation process with high purity and free of food additives and allergens.
Cognizin® is the only citicoline studied in humans in various age groups that can promote brain membrane turnover and energy utilization by the brain, in addition to improved attention span, physical performance, and memory.
Cognizin® citicoline supplementation, clinically tested for efficacy, can help mitigate cognitive decline associated with aging by playing a pivotal role in the 5 Brain Abilities:
Researchers observed increased brain activity among middle-aged adults who took Cognizin® , improving the turnover of essential membrane phospholipid components needed to synthesize and maintain cell membranes and brain bioenergetics through increased reserves and energy utilization.7
Cognizin®, taken daily, improves attention and concentration in healthy adult women after 28 days of daily supplementation. The women experienced fewer omission and commission errors compared to the placebo.3
Male adolescents who took Cognizin® observed an improvement in attention and a significant increase in psychomotor speed after 28 days of supplementation.4
Cognizin® can support memory, particularly episodic memory (in recalling events), as demonstrated in healthy older adults (50-85 years), after 12 weeks of supplementation.5
Therefore, in light of scientific research, Cognizin® is a highly effective and reliable form of citicoline that helps promote overall brain and neuronal tissue health for healthy cognitive function over time.
In Brain 5:5® HAP Body Brain Skin® has researched a precise daily dosage of Cognizin®, compatible with long-term dosing, aimed at supporting the 5 Brain Abilities through the synergistic combination of nootropic actives, all rigorously selected with the best efficacy and safety profiles.
Cognizin® is a registered trademark of KYOWA HAKKO BIO CO., LTD.
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