Resveratrol and Polydatin are both stilbenoids, which are naturally occurring polyphenols used by some plants as important defense weapons in response to stress, injury, infection, or UV radiation damage.
Beneficial to the human body as well, these two molecules claim extraordinary antioxidant and anti-inflammatory properties, exhibiting protection at the cellular and systemic levels for healthy living.
In addition to being critical in restoring the balance jeopardized by oxidative stress, they are valuable allies in fighting inflammaging and aging, due also to their ability to modulate sirtuin activation.
Sirtuins (known as “longevity proteins”) are proteins with essential enzymatic properties, produced by our body to regulate important biological processes (insulin resistance, energy metabolism, immunity control, inflammation defense, epigenetics, cardiac health, circadian rhythms, neurodegeneration), as well as cellular aging processes.
As effective “sentinels”, they are produced as a result of stimulation of SIRT genes (“longevity genes”) that are turned on in response to threats or metabolic stress conditions (e.g., starvation, cold, physical exertion). Overall, activation of SIRT genes aims to reduce cell replication to promote cell survival, consequently slowing down the aging process.
As early as 30-35 years of age, the body’s ability to naturally produce sirtuins decreases and consequently cells work less efficiently.
As a strategy to stimulate sirtuins and slow cellular aging, positively affecting quality of life over time, a mixture of naturally-derived stilbenoids, Resveratrol and Polydatin is particularly effective.
Well-known anti-aging actives, resveratrol and polydatin are “twin” molecules that differ from each other only in one glucose molecule: polydatin, as a glycosylated form, serves as a precursor to resveratrol, in which the addition of the sugar molecule gives it greater solubility and resistance to enzymatic attack (metabolic stability), ensuring better intestinal absorption. 1,2
In the formulation of a quality dietary supplement, such as Body 9:9®, it is therefore useful to take advantage of a combination of the active form (resveratrol, which once absorbed is metabolized and then eliminated very quickly) and its natural precursor (polydatin, up to 3-5 times more bioavailable than resveratrol)3 to exploit an advantageous interconversion after oral administration that can preserve the beneficial effects for the body.
In detail, in the Body 9:9® food supplement, the synergistic action between resveratrol and polydatin, partly due to the activation of sirtuins, results in multiple benefits against the major hallmarks of aging:
But that’s not all, in terms of health and wellbeing, for HAP Body Brain Skin®, the choice of innovative and high-performance ingredients that are carefully produced and such as to ensure unparalleled quality and high efficacy of the final formulations is also crucial:
In addition to the advantageous synergy of the two natural stilbenoids, Body 9:9® includes in its unique formulation one of the purest forms of resveratrol (>98%), obtained through an innovative fermentation and purification process from yeast that ensures the absence of hazardous contaminants, such as polycyclic aromatic hydrocarbons (PAHs), unfortunately still widespread in poor quality raw materials and extracts.
Actually, Veri-teTM trans-resveratrol (a special form of resveratrol that is biologically more active and better absorbed by the body) is supported by extensive research and offers proven benefits for health and cellular function.
A patented, multifunctional ingredient that has undergone rigorous testing to ensure consistently high quality and delivers on its promise of meeting wellness needs safely and with clinically proven benefits.
In the Body 9:9® food supplement, Veri-te™ resveratrol is combined with polydatin, which is also 98% pure, extracted from the root of Polygonum cuspidatum.
Veri-teTM is a trademark of Evolva SA.
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